First time trying this brand - the product is so light, goes on smoothly and easily and works great! Love the sheerness and the feel.
This new formulation layers well over other products. Hydrating but not sticky.
Lightweight Anti-Aging Gel for Firmer, Smoother, Radiant Skin
Experience advanced skin rejuvenation with ZO Skin Health Growth Factor Serum (30ml). This lightweight, fast-absorbing gel is designed to improve the appearance of fine lines, wrinkles, and loss of firmness. Powered by the innovative ZPRO® proprietary complex, this serum delivers plant-derived growth factors and biomimetic proteins that help support visible skin renewal and resilience.
Ideal for daily use, this luxurious formula helps restore a smoother, more youthful-looking complexion while enhancing skin elasticity and hydration.
30 mL / 1 fl oz.
Formerly known as Ossential® Growth Factor Serum Plus
ZO® Growth Factor Serum
Our Growth Factor Serum is a lightweight yet powerful formula designed to support your skin’s natural renewal process. It features two growth factors that actively promote collagen and elastin production, helping to improve skin density and firmness over time.
Additionally, a strategic blend of retinol and amino acids enhances cellular function, reduces collagen breakdown, and restores skin elasticity for a smoother, more youthful appearance. To further protect your skin, potent antioxidants defend against free radical damage, preventing future signs of aging and keeping your complexion looking healthy and resilient.
Perfect for those seeking a science-backed solution for aging skin, our Growth Factor Serum nourishes, strengthens, and revitalizes, ensuring long-term skin health and radiance.
93% of patients experienced improvements in fine lines and wrinkles, firmness and elasticity + texture and smoothness, after 12 weeks of using Growth Factor Serum. (see Before + After section for protocol)

Key Ingredients
Ingredients
Aqua/Water/Eau, Cyclopentasiloxane, Dipropylene Glycol, Propylene Glycol, Dimethicone, Glycerin, Dimethicone Crosspolymer, Dimethicone/PEG-10/15 Crosspolymer, PEG-12 Dimethicone Crosspolymer, Butylene Glycol, Dimethicone/Vinyl Dimethicone Crosspolymer, Sodium Phosphate, Panthenyl Triacetate, Phospholipids, Magnesium Sulfate, Hydrolyzed Sericin, Ethyl Linoleate, Buddleja Davidii Meristem Cell Culture, Angelica Polymorpha Sinensis Root Extract, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Lactobacillus/Panax Ginseng Root Extract Ferment Filtrate, Disodium Acetyl Glucosamine Phosphate, Acetyl Tyrosine, Dimethiconol, Oleyl Alcohol, Proline, Fragrance (Parfum), Tocopherol, Beta-Glucan, Adenosine Triphosphate, Hydrolyzed Vegetable Protein, Sodium Chloride, Xanthan Gum, Phenoxyethanol.
Apply 1–2 pumps to clean, dry skin morning and evening.
Allow the serum to absorb fully before applying moisturizer or sunscreen.
Warnings
For external use only. Avoid contact with eyes; if contact occurs, rinse thoroughly with water. Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Centre right away.
Recommended with Daily Power Defense and Growth Factor Eye Serum
This is an absolutely amazing product. It absolutely makes a difference.
I love all the ZO products. Regular use of this one seems to be good for my aging skin. Love the feel and the scent.
Excellent product, purchased again.
Thank you for your positive feedback on ZO Growth Factor Serum! We are thrilled to hear that you have had a great experience with our product and have purchased it again. We appreciate your support and look forward to providing you with more amazing products in the future. Thank you for choosing ZO!
Great
One of my favourites for evening!
Hi there! Thank you for your review and for sharing your experience with our ZO Growth Factor Serum. We're so happy to hear that it's one of your favorites for evening use. We strive to provide our customers with effective and high-quality products, so it means a lot to us that you are enjoying it. Thank you for choosing ZO and for being a valued customer. Have a great day!
This is an absolutely amazing product. It absolutely makes a difference.
I love all the ZO products. Regular use of this one seems to be good for my aging skin. Love the feel and the scent.
Excellent product, purchased again.
Thank you for your positive feedback on ZO Growth Factor Serum! We are thrilled to hear that you have had a great experience with our product and have purchased it again. We appreciate your support and look forward to providing you with more amazing products in the future. Thank you for choosing ZO!
Great
One of my favourites for evening!
Hi there! Thank you for your review and for sharing your experience with our ZO Growth Factor Serum. We're so happy to hear that it's one of your favorites for evening use. We strive to provide our customers with effective and high-quality products, so it means a lot to us that you are enjoying it. Thank you for choosing ZO and for being a valued customer. Have a great day!
First time trying this brand - the product is so light, goes on smoothly and easily and works great! Love the sheerness and the feel.
Great package, very well rounded products
This new formulation layers well over other products. Hydrating but not sticky.
First time trying this brand - the product is so light, goes on smoothly and easily and works great! Love the sheerness and the feel.
Great package, very well rounded products
Great deal on the products, received very quickly and good quality
This new formulation layers well over other products. Hydrating but not sticky.
The best exfoliant out there!