ZO Complexion Clarifying Serum (50ml)

Product image of ZO® Complexion Clarifying Serum "Breakout Buster" displayed side by side with ZO® Complexion Clearing Masque, showcasing a powerful duo designed to reduce breakouts, control excess oil, clear pores, and calm redness for visibly clearer, balanced skin

Product image of ZO® Complexion Clarifying Serum in sleek silver and white packaging, featuring a lightweight, water-based formula with Z-SEB3™ technology designed to reduce excess oil, clear congestion, and calm visible redness for a balanced complexion.

Close-up image of ZO® Complexion Clarifying Serum dropper with a droplet of serum falling, showcasing the lightweight, water-based texture formulated with Z-SEB3™ to reduce oil, clear pores, and calm visible redness

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ZO Complexion Clarifying Serum (50ml)

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ZO® Complexion Clarifying Serum (50ml)

Meet your new secret to consistently clear skin. ZO® Complexion Clarifying Serum is a lightweight, water-based formula powered by Z-SEB3™, an exclusive technology that targets excess oil, clogged pores, and visible redness. The result? A balanced, refined, and visibly calmer complexion—day after day. Clinically proven and fragrance-free, it delivers hydration without heaviness, making it ideal for oily, combination, and blemish-prone skin. Use it morning and night to maintain clarity, reduce shine, and support long-term skin health.

Appropriate for All Skin Types. Best for Oily + Blemish-Prone Skin.

Available in:

50 mL / 1.7 Fl. Oz.

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PRODUCT DESCRIPTION

Achieve a clear, shine-free complexion with ZO® Complexion Clarifying Serum, a water-based formula powered by ZSEB3™, ZO’s exclusive sebum-targeting technology. Clinically proven to reduce surface oil, congestion, and visible redness, this daily serum helps maintain a healthy, balanced skin barrier.

Has a unique dropper design that refills automatically, so it is easier to use, and avoids waste.

Ideal for combination, oily, and blemish-prone skin, it provides hydration without clogging pores—leaving skin feeling refreshed, smooth, and clarified.

Fragrance-free + alcohol-free for gentle, effective results. Light weight gel formula.

Key Benefits

✔ Controls excess oil – Reduces surface shine for a fresh, matte look. Proven to decongest the skin in 2 weeks.
✔ Minimizes congestion and excess sebum – Helps clear pores to prevent breakouts.
✔ Soothes visible redness – Calms skin for an even-toned complexion.
✔ Lightweight hydration – Keeps skin balanced without feeling greasy.

Clinically Proven Results

What's Inside

Key Ingredients:

ZO® Sebum Targeting Complex (Eugenia uniflora leaf extract, Syringa vulgaris extract, Rosa Canina extract)

Minimizes excess surface sebum and helps promote a balanced microbiome for a clear + shine-free complexion

Water-Soluble Salicylic Acid

Powerfully decongests skin + refines the look of pores in a gentle, non-drying delivery

ZO-RRS2®

Exclusive plant stem cell complex that soothes visible redness while neutralizing damaging free radicals

ZPOLY™

Exclusive plant-derived polysaccharide complex that supports skin’s protective barrier + helps minimize signs of premature skin aging

All Ingredients:

Aqua/Water/Eau, Propanediol, Glycerin, Salicylic Acid, Sodium Polyacrylate, Butylene Glycol, Eugenia Uniflora Leaf Extract, Laminaria Digitata Extract, Rosa Canina Fruit Extract, Syringa Vulgaris (Lilac) Extract, Opuntia Ficus-Indica Stem Extract, Leontopodium Alpinum Meristem Cell Culture, Marrubium Vulgare Meristem Cell Culture, Lecithin, Galactoarabinan, Schizophyllan, Maltodextrin, Caprylyl Glycol, Phytic Acid, Trisodium Ethylenediamine Disuccinate, Inulin Lauryl Carbamate, Acacia Senegal Gum, Xanthan Gum, Mannitol, Sodium Citrate, Hydroxyacetophenone, Trehalose, Sodium Bisulfite, Ergothioneine, Phenoxyethanol, Chlorphenesin, Benzyl Alcohol, Potassium Sorbate, Sodium Benzoate. We are continually innovating and adapting to new regulations. As a result, depending on when and where the product was purchased, the ingredient lists on this website may differ from product packaging. Please refer to your product packaging for ingredient information specific to your product.

How to Use

Directions

Apply to clean, dry skin morning and night.

Protocol

A 6-week independent, third-party clinical evaluation of 43 female subjects to test the efficacy of Complexion Clarifying Serum. Subjects represented females ages 16 to 44 with Fitzpatrick skin types II-IV. Analysis conducted via Sebumeter® SM, Expert Grader and VISIA ® CR. Supported with the use of Gentle Cleanser and Broad-Spectrum Sunscreen SPF 50 throughout the study.

Better Results with Complexion Renewal Pads, Exfoliating Cleanser, Daily Power Defense and Broad-Spectrum Sunscreen